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5-Amino-1MQ

5-Amino-1MQ – 30 mg is a research-grade small-molecule compound studied as an inhibitor of nicotinamide N-methyltransferase (NNMT). It is intended for controlled laboratory research involving NAD+ metabolism, methylation pathways, cellular metabolism, and NNMT-related signaling.

Price range: £ 29.99 through £ 59.99

Safety & Compliance

In-Vitro Classification
This specimen is synthesized strictly for In-Vitro Research Applications. Any deviation from documented laboratory protocol is strictly prohibited.

[01]   Not for human or animal consumption
[02]   Restricted laboratory use only

Product Discription

5-Amino-1MQ, also known as 5-amino-1-methylquinolinium, is a synthetic quinolinium-based small molecule investigated as an inhibitor of nicotinamide N-methyltransferase (NNMT). Unlike the peptide compounds in the Amino Labs catalogue, 5-Amino-1MQ is a small molecule and does not contain an amino-acid peptide backbone. NNMT is an enzyme involved in the metabolism of nicotinamide and S-adenosylmethionine (SAM), linking it to cellular NAD+ and methylation pathways. 5-Amino-1MQ has therefore attracted research interest as a chemical tool for investigating NNMT activity and related metabolic processes. The 30 mg presentation is intended for qualified research environments conducting controlled investigations into NNMT enzymology, NAD+ metabolism, methylation biology, cellular metabolism, and related biochemical pathways.

Key Features

30 mg research-grade 5-Amino-1MQ 5-amino-1-methylquinolinium Small-molecule NNMT inhibitor Relevant to NAD+ and methylation research Suitable for biochemical and cellular research Intended for controlled laboratory research Appropriate for enzyme-inhibition and metabolic pathway studies Suitable for analytical characterization and batch-level documentation Research Focus 5-Amino-1MQ has been investigated as a tool compound for studying NNMT inhibition and its relationship to cellular nicotinamide metabolism. Preclinical research has examined NNMT activity in biochemical, cell-culture, and animal models, making 5-Amino-1MQ relevant to metabolic and enzymology research. The available evidence for 5-Amino-1MQ remains predominantly preclinical, with no established human clinical efficacy or safety profile. Accordingly, its use is best described in the context of laboratory investigation rather than therapeutic application.

Important Notice

This product is supplied strictly for research and laboratory use. It is not intended for human or veterinary use, self-administration, consumption, diagnosis, treatment, or prevention of disease. 5-Amino-1MQ is a research chemical rather than a peptide or approved pharmaceutical product and should be handled only by appropriately qualified personnel in accordance with applicable laboratory protocols and regulations.
Molecular Formula

C10H11N2 (cation); commonly supplied as a chloride/iodide salt

Molecular Weight

159.21 g/mol (free cation); salt forms are higher

Storage Information

Store lyophilized powder at -20°C (stable 24+ months); short-term storage 2-8°C. Once reconstituted, use within 7-14 days and avoid repeated freeze-thaw.

Research Information

Small-molecule, selective nicotinamide N-methyltransferase (NNMT) inhibitor. Studied for adipocyte lipogenesis, diet-induced obesity, and muscle-regeneration research in mouse models.

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